Fifteen minutes after receiving sulfamethoxazole-trimethoprim, a client reports a burning sensation in multiple areas. What intervention is most important?

• A. Auscultate lung sounds for wheezing
• B. Administer an antacid
• C. Provide a warm blanket
• D. Offer water to drink slowly

Answer: (A)

The most important focus is the airway and breathing status. A burning sensation after starting a drug like sulfamethoxazole-trimethoprim can be an early sign of a hypersensitivity reaction that may progress to anaphylaxis. The top priority is to assess for airway involvement, such as bronchospasm, which shows up as wheezing on lung auscultation. Detecting wheezing indicates the patient may be developing life-threatening airway compromise and needs rapid, emergency treatment (such as epinephrine, oxygen, and close monitoring).

Other choices do not address potential airway obstruction or the immediate threat to breathing. An antacid won’t help a suspected allergic reaction, a warm blanket doesn’t treat airway issues or shock, and offering water could delay necessary care or pose a risk if the patient is unable to swallow safely.